Drug-induced immune hemolytic anemia is a blood disorder that occurs when a medicine triggers the body's defense (immune) system to attack its own red blood cells. This type is often inherited. This causes red blood cells to break down earlier than normal, a process called hemolysis. Hemolytic anemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). This can cause seizures, brain damage, and deafness. Case summary: An 83-year-old white woman developed persistent hyperpyrexia, polyarthralgia, and lower limb hypostenia about 2 days after receiving influenza vaccine. Hemolytic anemia is defined by the premature destruction of red blood cells, and can be chronic or life-threatening. Hemolytic anemias. This causes your baby’s liver to grow too big. He or she will still have anemia. Sometimes, the causes of hemolytic anemia are unclear, but they can include: An attack by your immune system , as with lupus . Hemolytic anemia and the underlying cause is easy to diagnose, but there are instances where the causes of hemolytic anemia are unknown. Causes of and Risk Factors for Hemolytic Anemia There are two major types of hemolytic anemia: Congenital hemolytic anemia is a condition in which … Hemolytic anemia has multiple causes, and the clinical presentation can differ depending on the etiology. Certain blood diseases increase red blood cell destruction. This is when the destruction of red blood cells is due to a flaw within the red blood cells. Hemolytic anemia has 2 types of causes: Intrinsic. This is the most severe form of hyperbilirubinemia. You can inherit a hemolytic anemia, or you can develop it later in life. What causes hemolytic anemia in a child? Infectious organisms may cause hemolytic anemia through the direct action of toxins (eg, Clostridium perfringens, alpha- or beta-hemolytic streptococci, meningococci), by invasion and destruction of the RBC by the organism (eg, Plasmodium species, Bartonella species,Babesia species) or by antibody production (eg, Epstein-Barr virus, mycoplasma). An array of laboratory tests are available for detecting hemolysis, and specialized tests may be indicated to diagnose the cause for hemolysis (see Workup). It includes sickle cell anemia, thalassemia, or erythrocytosis. This most commonly occurs within the spleen, but also can occur in the reticuloendothelial system or mechanically (prosthetic valve damage). It’s because of the buildup of bilirubin in your baby’s brain. Immune-mediated hemolytic anemia (IMHA) is one of the more commonly encountered causes of anemia in dogs and cats. This can happen to anyone, even a baby still in the womb or a newborn. Objective: To describe 2 cases of autoimmune hemolytic anemia (AIHA) following the administration of MF59-adjuvanted influenza vaccine. IMHA can affect animals of any age, but it most commonly affects young adult and middle-aged dogs and cats. Clinical signs and laboratory evaluations suggested AIHA. Hemolytic anemia is a disorder in which red blood cells are destroyed faster than they are made. This inherited and sometimes serious condition is a hemolytic anemia. Kernicterus. Treatment of hemolytic anemia largely depends on the underlying disease causing the anemia and on the disease severity. Sickle cell anemia. Here's what you need to know. It can even cause death. This group of anemias develops when red blood cells are destroyed faster than bone marrow can replace them.
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